Guess I just need more detail.
I am using Windows 7, and use the Babyface RME as my external audio interface. It works with all my Native Instruments programs without a hitch. I can hear my guitar through my monitor speakers. I can see the input levels moving as I play. I just can't get Yousician to hear anything.
Have my guitar cable plugged directly into the side of the unit in the analog guitar input jack. Like I said, it is getting a signal to the AN 1+2 input (analog). I have it set to INST and I also have it set to loopback. In Yousician, I have the recording device set to AN 1+2 RME. Nothing. Tuner can't hear it. Songs can't hear it.
I am trying to use Babyface, as my Rocksmith cable produced latency so bad, that I would have to play every note a half second early for the software to like my timing. Mind you, there is zero latency issues with Rocksmith. Terrible on the chord section (gave up). If it works on a couple pieces of software and only has latency issues in Yousician, I logically have to assume the issue is with the programming in Yousician's software.
So I figured a $700 external audio interface would do the trick. Nope.
Love the layout of Yousician compared to Rocksmith, but the experience so far has left me...not so happy or impressed. If I can get this to work without latency and recognize the all-important fact that I am playing an instrument, this will likely be excellent software. But so far, two audio interfaces not communicating with ease, to software that relies on this connection is a major flaw.
Hopefully someone out there can help me out with this.